Thyroid Peroxidase | TPO | Anti TPO Antibodies | Thyroid Antibodies |

Thyroid peroxidase, also called thyroperoxidase (TPO) or iodide peroxidase, is an enzyme expressed mainly in the thyroid.

Thyroid peroxidase oxidizes iodide ions to form iodine atoms for addition onto tyrosine residues on thyroglobulin for the production of thyroxine (T4) or triiodothyronine (T3), the thyroid hormones.

In humans, thyroperoxidase is encoded by the TPO gene.

Thyroid peroxidase is a frequent epitope of autoantibodies in autoimmune thyroid disease, ..autoantibodies like anti-thyroid peroxidase antibodies (anti-TPO antibodies).

This is most commonly associated with Hashimoto’s thyroiditis. Thus, an antibody titer can be used to assess disease activity in patients that have developed such antibodies.
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Learn what it means to have high thyroid antibodies and what you need to do.
Thyroid presentation referenced-
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